Avoid Leaving Your Pet Alone
This is a general tip a lot of people end up forgetting about when they bring their pet with them on vacation. Remember that you brought them with you for a reason, so don't just keep them inside all day while you go off and explore. If you bring them with you on a trip, you'll need to make sure a lot of the activities you plan to do are pet-friendly. Let them experience the rejuvenation of a good vacation just like you. If you keep them entertained, you reduce the chances of something going wrong.
Find a Reliable Vet
When you go anywhere away from home and you can't get to your normal vet, you need to ensure there is a vet you can go to instead. Check out the different vet clinics in the area you will visit, and make sure they can treat your four-legged friends. Hopefully it won't be necessary, but it's a precaution you must take.